Calcium Handling in hiPSC-Derived Cardiomyocytes

Author(s): Lee Yee-Ki; Siu Chung-Wah
Publisher: Springer
ISBN: 9781461440925
Edition:

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Description

Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.